Article
Experimental keratitis induced in rat by Acanthamoeba from distinct morphological groups/genotypes: a histological and immunohistochemical evaluation.
Parasitology research - 1 May 2023
de Souza Fernandes Norberto, Caliari Marcelo Vidigal, Oliveira Fabricio Marcos Silva, Neto Alexandre Batista Costa, Rodrigues Isabela Aurora, Furst Cinthia, Costa Adriana Oliveira
Abstract excerpt
Species of the genus Acanthamoeba are free-living protozoans that occasionally act as parasites, causing a severe, progressive corneal infection termed Acanthamoeba keratitis (AK). The variable pathogenic potential among Acanthamoeba lineages has been shown by in vitro assays, but little is known about the behavior of different strains in animal models of AK. This work aimed to evaluate the infectivity of...
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