Article
Altered Differential Expression of Genes and microRNAs Related to Adhesion and Apoptosis Pathways in Patients with Different Phenotypes of Endometriosis.
International journal of molecular sciences - 23 Feb 2023
Antonio Luana Grupioni Lourenço, Meola Juliana, Rosa-E-Silva Ana Carolina Japur de Sá, Nogueira Antonio Alberto, Candido Dos Reis Francisco José, Poli-Neto Omero Benedicto, Rosa-E-Silva Julio César
Abstract excerpt
We aim to investigate the expression of genes (MAPK1 and CAPN2) and microRNAs (miR-30a-5p, miR-7-5p, miR-143-3p, and miR-93-5p) involved in adhesion and apoptosis pathways in superficial peritoneal endometriosis (SE), deep infiltrating endometriosis (DE), and ovarian endometrioma (OE), and to evaluate whether these lesions share the same pathophysiological mechanisms. We used samples of SE (n = 10), DE (n = 10),...
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