Article
Synergic Action of Insulin-like Growth Factor-2 and miRNA-483 in Pterygium Pathogenesis
22 Feb 2023
Abstract excerpt
Pterygium is a multifactorial disease in which UV-B is speculated to play a key role by inducing oxidative stress and phototoxic DNA damage. In search for candidate molecules that are useful for justifying the intense epithelial proliferation observed in pterygium, our attention has been focused on Insulin-like Growth Factor 2 (IGF-2), mainly detected in embryonic and fetal somatic tissues, which regulate...
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