Genetic distance analysis using DNA polymorphisms in the alpha-globin gene cluster.

doi:10.1080/03014468700009211

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Genetic distance analysis using DNA polymorphisms in the alpha-globin gene cluster.

Annals of human biology - 1 Jan 2000

Summers K M, Yenchitsomanus P, Chapple R M

Abstract excerpt

Published frequencies for alleles at the alpha- and zeta-globin gene loci within the alpha-globin gene cluster were used to calculate genetic distances between populations of South East Asia and the Pacific region. When analyses using the alpha-globin alleles, populations are grouped according to the endemicity of malaria while the groupings derived from the embryonic zeta-globin allele frequencies appear to be...

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