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Inoculation with ASFV-Katanga-350 Partially Protects Pigs from Death during Subsequent Infection with Heterologous Type ASFV-Stavropol 01/08.

Viruses - 3 Feb 2023

Vlasov Mikhail E, Sindryakova Irina P, Kudrjashov Dmitry A, Morgunov Sergey Y, Kolbasova Olga L, Lyska Valentina M, Zhivoderov Sergey P, Pivova Elena Y, Balyshev Vladimir M, Sereda Alexey D, Kolbasov Denis V

Abstract excerpt

African swine fever virus (ASFV) is an extremely genetically and phenotypically heterogeneous pathogen. Previously, we have demonstrated that experimental inoculation of pigs with an attenuated strain, Katanga-350 (genotype I, seroimmunotype I) (ASFV-Katanga-350), can induce protective immunity in 80% of European domestic pigs against the homologous virulent European strain Lisbon-57. At least 50% of the...

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PMID: 36851644
DOI: 10.3390/v15020430
PMCID: PMC9959532

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