Article
A durable response to savolitinib in a patient with lung adenocarcinoma harboring two novel MET exon 14 skipping sites.
Anti-cancer drugs - 1 Sept 2023
Gu Linping, Zhao Yi, Wen Fengcai, Zhang Ding, Cai Jinping, Chen Zhiwei
Abstract excerpt
MET exon 14 ( METex14 ) skipping variants are oncogenic drivers in non-small-cell lung cancer. Several METex14 skipping alterations have been identified, but different mesenchymal-epithelial transition (MET) exon splicing variants tend to present different clinical outcomes. Here, we reported that a patient with lung adenocarcinoma harbored two novel METex14 skipping mutations (c.2888-35_2888-16del and...
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