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Comparative Pharmacological Efficacy of COVID-19 Vaccines against the Variants of Concerns (VOCs) of SARS-CoV-2: Recent Clinical Studies on Booster Dose.

Current pharmaceutical biotechnology - 1 Jan 2023

Zhao Di, Wang Xiaoyan, Liu Junqi, Au Chinnappa, Basavaraj Vijaya, Sri Chiriki Devi, Nikolenko Vladimir N, Beeraka Narasimha M, Shivaprakash Priyanka, Fan Ruitai

Abstract excerpt

Sera obtained from convalescent individuals, and vaccinated individuals can induce low neutralizing efficacy against variants of concerns (VOCs) of SARS-CoV-2. In addition, the majority of COVID-19 vaccines are less efficacious against VOCs when compared to their efficacy against the original virus. Immune escape is one of the significant mechanisms observed during SARS-CoV-2 infection due to the substantial...

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PMID: 36843370
DOI: 10.2174/1389201024666230227115329

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