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Detection and characterization of the novel HLA-DPA1*02:66:02N allele, with a premature stop codon in exon 2.

Human immunology - 1 Apr 2023

Niño Ramírez Jairo Eduardo, Balas Antonio, Gil-Etayo Francisco Javier, Jiménez Hernaz Isabel, Terradillos Sánchez Pilar, Vicente Parra Ariadna, Balanzategui Ana, Alcoceba Miguel, García Sanz Ramón, Tejeda Velarde Amalia

Abstract excerpt

The failure to identify HLA null alleles in bone marrow transplantation could be life-threatening because this could result in an HLA mismatch with the ability to trigger the graft-vs-host disease (GVHD) and to reduce patient's survival. In this report we describe the identification and characterization of the novel HLA-DPA1*02:66:02N allele with a non-sense codon in exon 2. This new allele was discovered in two...

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PMID: 36797092
DOI: 10.1016/j.humimm.2023.02.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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