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Article

EGFR-TKI Combined with Pemetrexed versus EGFR-TKI Monotherapy in Advanced EGFR-mutated NSCLC: A Prospective, Randomized, Exploratory Study.

Cancer research and treatment - 1 Jul 2023

Gu Weiguang, Zhang Hua, Lu Yiyu, Li Minjing, Yang Shuang, Liang Jianmiao, Ye Zhijian, Li Zhihua, He Minhong, Shi Xiaoliang, Wang Fei, You Dong, Gu Weiquan, Feng Weineng

Abstract excerpt

PURPOSE: We aimed to evaluate whether the addition of pemetrexed is effective in improving progression-free survival (PFS) in epidermal growth factor receptor (EGFR)-mutated patients with or without concomitant alterations. Materials and Methods: This multicenter clinical trial was conducted in China from June 15, 2018, to May 31, 2019. A total of 92 non-small cell lung cancer (NSCLC) patients harboring...

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Identifiers

PMID: 36791768
DOI: 10.4143/crt.2022.1438
PMCID: PMC10372607

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