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Article

The role of brain radiotherapy for EGFR- and ALK-positive non-small-cell lung cancer with brain metastases: a review.

La Radiologia medica - 1 Mar 2023

Nardone Valerio, Romeo Caterina, D'Ippolito Emma, Pastina Pierpaolo, D'Apolito Maria, Pirtoli Luigi, Caraglia Michele, Mutti Luciano, Bianco Giovanna, Falzea Antonella Consuelo, Giannicola Rocco, Giordano Antonio, Tagliaferri Pierosandro, Vinciguerra Claudia, Desideri Isacco, Loi Mauro, Reginelli Alfonso, Cappabianca Salvatore, Tassone Pierfrancesco, Correale Pierpaolo

Abstract excerpt

Non-small cell lung cancer (NSCLC) is frequently complicated by central nervous system (CNS) metastases affecting patients' life expectancy and quality. At the present clinical trials including neurosurgery, radiotherapy (RT) and systemic treatments alone or in combination have provided controversial results. CNS involvement is even more frequent in NSCLC patients with EGFR activating mutations or ALK...

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Identifiers

PMID: 36786970
DOI: 10.1007/s11547-023-01602-z
PMCID: PMC10020247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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