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Article

Complete functional analysis of type IV pilus components of a reemergent plant pathogen reveals neofunctionalization of paralog genes.

PLoS pathogens - 1 Feb 2023

Merfa Marcus V, Zhu Xinyu, Shantharaj Deepak, Gomez Laura M, Naranjo Eber, Potnis Neha, Cobine Paul A, De La Fuente Leonardo

Abstract excerpt

Type IV pilus (TFP) is a multifunctional bacterial structure involved in twitching motility, adhesion, biofilm formation, as well as natural competence. Here, by site-directed mutagenesis and functional analysis, we determined the phenotype conferred by each of the 38 genes known to be required for TFP biosynthesis and regulation in the reemergent plant pathogenic fastidious prokaryote Xylella fastidiosa. This...

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Identifiers

PMID: 36780566
DOI: 10.1371/journal.ppat.1011154
PMCID: PMC9956873

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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