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Article

Potential upstream lncRNA–miRNA–mRNA regulatory network of the ferroptosis-related gene SLC7A11 in renal cell carcinoma

1 Jan 2023

Abstract excerpt

Background: SLC7A11 is a key regulator of ferroptosis, which mediates cysteine uptake for glutathione biosynthesis and maintains redox homeostasis. Emerging evidence has shown that SLC7A11 is upregulated in many human tumors. Nevertheless, the prognosis and posttranslational regulatory mechanism of SLC7A11 in renal cell carcinoma (RCC) remains obscure. Methods: The Oncomine, Gene Expression Profiling Interactive...

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PMID: 36760866
DOI: 10.21037/tau-22-663

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