Article
Recent Developments and Challenges in Molecular-Targeted Therapy of Non-Small-Cell Lung Cancer.
Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer - 1 Jan 2023
Rohilla Suman, Singh Mahaveer, Alzarea Sami I, Almalki Waleed Hassan, Al-Abbasi Fahad A, Kazmi Imran, Afzal Obaid, Altamimi Abdulmalik Saleh Alfawaz, Singh Sachin Kumar, Chellappan Dinesh Kumar, Dua Kamal, Gupta Gaurav
Abstract excerpt
Treatment of lung cancer with conventional therapies, which include radiation, surgery, and chemotherapy results in multiple undesirable adverse or side effects. The major clinical challenge in developing new drug therapies for lung cancer is resistance, which involves mutations and disturbance in various signaling pathways. Molecular abnormalities related to epidermal growth factor receptor (EGFR), v-Raf murine...
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