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Highly Pathogenic Avian Influenza H5N1 Virus Infections in Wild Red Foxes (Vulpes vulpes) Show Neurotropism and Adaptive Virus Mutations.

Microbiology spectrum - 14 Feb 2023

Bordes Luca, Vreman Sandra, Heutink Rene, Roose Marit, Venema Sandra, Pritz-Verschuren Sylvia B E, Rijks Jolianne M, Gonzales José L, Germeraad Evelien A, Engelsma Marc, Beerens Nancy

Abstract excerpt

During the 2020 to 2022 epizootic of highly pathogenic avian influenza virus (HPAI), several infections of mammalian species were reported in Europe. In the Netherlands, HPAI H5N1 virus infections were detected in three wild red foxes (Vulpes vulpes) that were submitted with neurological symptoms between December of 2021 and February of 2022. A histopathological analysis demonstrated that the virus was mainly...

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PMID: 36688676
DOI: 10.1128/spectrum.02867-22
PMCID: PMC9927208

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