Article
Molecular phenotypes of bovine blastocyst derived from in vitro-matured oocyte supplemented with PAPP-A.
Veterinary research communications - 1 Sept 2023
Dellaqua Thaisy Tino, Franchi Fernanda Fagali, Dos Santos Priscila Helena, Giroto Alan Brunholi, Nunes Sarah Gomes, de Lima Victor Augusto Vieira, Guilherme Vitória Bertogna, Fontes Patrícia Kubo, Sudano Mateus José, de Souza Castilho Anthony César
Abstract excerpt
Insulin-like growth factor-1 (IGF-1) regulates cellular lipid content, whereas pregnancy-associated plasma protein-A (PAPP-A) increases IGF-1 bioavailability. Using in vitro-matured cumulus-oocyte complexes, we aimed to evaluate the impact of PAPP-A on the blastocyst lipid content, embryo cryotolerance and embryonic transcriptional profile. We determined that PAPP-A did not affect the lipid content of oocytes,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.