Differential protein expression of GABA A receptor alpha 1 subunit and calbindin in rat spermatozoa associated with proteomic analysis in testis following methamphetamine administration

Abstract excerpt

Methamphetamine (METH) can induce spermatogenesis impairment, testicular apoptosis, and abnormal sperm quality. It also promotes changes in the expression of receptors for sex hormones and neurotransmitters, including GABA receptors in the testis. Proteomic assessment focusing on proteins involved in the calcium signalling pathway in the testis can facilitate diagnostic factors contributing to testicular and...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Reproductive Biology and Fertility
• Share to RNA Interference and Gene Delivery
• Share to Sperm and Testicular Function