Article
Assessment of high-risk human papillomavirus infections and associated cervical dysplasia in HIV-positive pregnant women in Germany: a prospective cross-sectional two-centre study.
Archives of gynecology and obstetrics - 1 Jul 2023
Metz Charlotte K, Skof Anna S, Sehouli Jalid, Siedentopf Jan-Peter, Gebert Pimrapat, Weiss Fabian, Alba Alejandre Irene, Heinrich-Rohr Michaela, Weizsaecker Katharina, Henrich Wolfgang, Kaufmann Andreas M, Rohr Irena
Abstract excerpt
PURPOSE: Invasive cervical cancer (ICC) is associated in nearly 100% with persistent high-risk Human Papillomavirus (HR-HPV) infection. ICC is still one of the leading causes for cancer mortality in women worldwide. The immunosuppressive influence of Human Immunodeficiency Virus (HIV) and the immunocompromised period of pregnancy due to tolerance induction against the hemiallogeneic fetus, are generally risk...
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