The Coming of Age of Topical Gene Therapy for Dystrophic Epidermolysis Bullosa

Abstract excerpt

Dystrophic epidermolysis bullosa is a genetic disorder in which there is a loss of anchoring fibrils and structural integrity in the superficial layers of the dermis owing to mutations in the gene encoding type VII collagen (COL7A1), as explained by Payne in this issue of the Journal.1 This process leads to the development of painful skin blisters along with a range of secondary illnesses.2 The condition can be...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Autoimmune Bullous Skin Diseases
• Share to Hair Growth and Disorders
• Share to Skin and Cellular Biology Research