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Measurable residual disease in chronic myeloid leukemia

1 Dec 2022

Abstract excerpt

Chronic myeloid leukemia is characterized by a single genetic abnormality resulting in a fusion gene whose mRNA product is easily detected and quantified by reverse-transcriptase polymerase chain reaction analysis. Measuring residual disease was originally introduced to identify patients relapsing after allogeneic stem cell transplantation but rapidly adopted to quantify responses to tyrosine kinase inhibitors....

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PMID: 36453517
DOI: 10.3324/haematol.2022.281493

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