Article
Familial risk of psychosis in obsessive-compulsive disorder: Impact on clinical characteristics, comorbidity and treatment response.
Journal of psychiatric research - 1 Dec 2022
Balachander Srinivas, Thatikonda Navya Spurthi, Kannampuzha Anand Jose, Bhattacharya Mahashweta, Sheth Sweta, Ramesh Vinutha, Chandy Alexander Alen, Muthukumaran Moorthy, Joseph Mino Susan, Selvaraj Sowmya, Ithal Dhruva, Sreeraj Vanteemar S, John John P, Venkatasubramanian Ganesan, Viswanath Biju, Reddy Yc Janardhan, Jain Sanjeev
Abstract excerpt
BACKGROUND: Family studies in obsessive-compulsive disorder (OCD) indicate higher rates of psychosis among their first-degree relatives (FDRs). However, the etiological and clinical relationships between the two disorders remain unclear. We compared the clinical characteristics and pharmacological treatment response in patients diagnosed with OCD with a family history of psychosis (OCD-FHP), with a family history...
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