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The role of a cuproptosis-related prognostic signature in colon cancer tumor microenvironment and immune responses

12 Oct 2022

Abstract excerpt

Background: Colon adenocarcinoma (COAD) is a common malignant tumor of the digestive tract with poor clinical outcomes. Cuproptosis is a novel cell death mechanism and linked to mitochondrial respiration. However, the role of cuproptosis in colon cancer tumor microenvironment (TME) and immune responses remains unknown. Methods: We conducted difference analysis to identify the differential expressed...

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PMID: 36313449
DOI: 10.3389/fgene.2022.928105

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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