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N-glycosylation of cervicovaginal fluid reflects microbial community, immune activity, and pregnancy status

10 Oct 2022

Abstract excerpt

Human cervicovaginal fluid (CVF) is a complex, functionally important and glycan rich biological fluid, fundamental in mediating physiological events associated with reproductive health. Using a comprehensive glycomic strategy we reveal an extremely rich and complex N-glycome in CVF of pregnant and non-pregnant women, abundant in paucimannose and high mannose glycans, complex glycans with 2-4 N-Acetyllactosamine...

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PMID: 36216861
DOI: 10.1038/s41598-022-20608-7

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