Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MEF2C-AS1 regulates its nearby gene MEF2C to mediate cervical cancer cell malignant phenotypes in vitro.

Biochemical and biophysical research communications - 3 Dec 2022

Guo Qi, Zhang Lijia, Zhao Lei, Pang Xueying, Wang Peng, Sun Heng, Liu Songjiang

Abstract excerpt

Cervical cancer (CC) is the second most common malignancy among women. GEPIA demonstrated that MEF2C-AS1 and its nearby gene MEF2C present downregulation in CC tissues. We attempted to clarify molecular mechanism between MEF2C-AS1 and MEF2C underlying CC progression. RT-qPCR was used to measure expression levels and subcellular distribution of MEF2C-AS1 and MEF2C in CC cell lines. Gain-of-function assays were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Line, Tumor
Share to Cell Proliferation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to MEF2 Transcription Factors

Share to MicroRNAs

Share to Phenotype

Share to RNA, Long Noncoding

Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 36198203
DOI: 10.1016/j.bbrc.2022.09.091

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MEF2C-AS1 regulates its nearby gene MEF2C to mediate cervical cancer cell malignant phenotypes in vitro.PMID 36198203Read ↗

Study on the regulatory mechanism of EAF2 in the microenvironment of cervical cancerSemantic proximity Read ↗

Expression and gene regulation network of EAF2 in cervical cancer based on data miningSemantic proximity Read ↗

High expression of KIF4A predicts poor prognosis hallmark and is correlated with immune infiltrates in cervical cancerSemantic proximity Read ↗

Pseudogene CIDECP inhibits the migration and invasion of cervical cancer cells through the miR-29a-3p /NFATC4 axisSemantic proximity Read ↗

miR‑140‑5p inhibits cervical cancer cell phenotypes via downregulating FEN1 to halt the cell cycle.Semantic proximity Read ↗

Combining Bioinformatics and Experiments to Identify and Verify Key Genes with Prognostic Values in Endometrial CarcinomaSemantic proximity Read ↗

CircAGFG1 promotes cervical cancer progression via miR-370-3p/RAF1 signalingSemantic proximity Read ↗

FBXO5 acts as a novel prognostic biomarker for patients with cervical cancerSemantic proximity Read ↗

EBP50 interacts with EGFR and regulates EGFR signaling to affect the prognosis of cervical cancer patientsSemantic proximity Read ↗

Systematic Analysis of the Clinical Relevance of Cell Division Cycle Associated Family in Endometrial CarcinomaSemantic proximity Read ↗

Circ-CCDC66 upregulates REXO1 expression to aggravate cervical cancer progression via restraining miR-452-5pSemantic proximity Read ↗

miRNAs role in cervical cancer pathogenesis and targeted therapy: Signaling pathways interplaySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.