Identification of key snoRNAs serves as biomarkers for hepatocellular carcinoma by bioinformatics methods

Abstract excerpt

BACKGROUND: Hepatocellular carcinoma (HCC) is a common malignancy with high mortality and poor prognosis due to a lack of predictive markers. However, research on small nuclear RNAs (snoRNAs) in HCC were very little. This study aimed to identify a potential diagnostic and prognostic snoRNA signature for HCC. METHODS: HCC datasets from the cancer genome atlas (TCGA) and international cancer genome consortium...

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