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DNA methylation alterations caused by Leishmania infection may generate a microenvironment prone to tumour development

29 Aug 2022

Abstract excerpt

DNA methylation is an epigenetic signature consisting of a methyl group at the 5’ cytosine of CpG dinucleotides. Modifications in DNA methylation pattern have been detected in cancer and infectious diseases and may be associated with gene expression changes. In cancer development DNA methylation aberrations are early events whereas in infectious diseases these epigenetic changes may be due to host/pathogen...

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PMID: 36105147
DOI: 10.3389/fcimb.2022.984134

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