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Article

Comprehensive analysis of pyroptotic gene prognostic signatures associated with tumor immune microenvironment and genomic mutation in breast cancer.

Frontiers in immunology - 1 Jan 2022

Zhang Hongfei, Yu Xiafei, Yang Junzhe, He Gao, Zhang Xiaoqiang, Wu Xian, Shen Li, Zhou Yi, Cheng Xuyu, Liu Xiaoan, Zhu Yanhui

Abstract excerpt

Background: Breast cancer is becoming a tumor with the highest morbidity rate, and inflammation-induced cell death namely pyroptosis reportedly plays dual roles in cancers. However, the specific mechanism between pyroptosis and the clinical prognosis of breast cancer patients is indistinct. Hence, novel pyroptosis-related biomarkers and their contributing factors deserve further exploration to predict the...

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Identifiers

PMID: 36090993
DOI: 10.3389/fimmu.2022.933779
PMCID: PMC9453314

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