Article
Druggable gene alterations in Japanese patients with rare malignancy.
Neoplasia (New York, N.Y.) - 1 Nov 2022
Ohmoto Akihiro, Hayashi Naomi, Fukada Ippei, Yamazaki Masumi, Yunokawa Mayu, Kasuga Akiyoshi, Shinozaki Eiji, Ueki Arisa, Tonooka Akiko, Takeuchi Kengo, Mori Seiichi, Kiyotani Kazuma, Takahashi Shunji
Abstract excerpt
Without a current standard of care, patients with rare malignancy are subjected to precision oncology with next-generation sequencing to identify a course of treatment. We sought to establish the clinical relevance of comprehensive genomic profiling (CGP) among patients with rare malignancy. Rare malignancy was defined using the Rare Cancers in Europe definition (<6 cases per 100,000 individuals). We analyzed...
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