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Fast and accurate kinship estimation using sparse SNPs in relatively large database searches.

Forensic science international. Genetics - 1 Nov 2022

Snedecor June, Fennell Tim, Stadick Seth, Homer Nils, Antunes Joana, Stephens Kathryn, Holt Cydne

Abstract excerpt

Forensic genetic genealogy (FGG) has primarily relied upon dense single nucleotide polymorphism (SNP) profiles from forensic samples or unidentified human remains queried against online genealogy database(s) of known profiles generated with SNP microarrays or from whole genome sequencing (WGS). In these queries, SNPs are compared to database samples by locating contiguous stretches of shared SNP alleles that...

Topics

Humans
Polymorphism, Single Nucleotide
Pedigree
Alleles
Polymerase Chain Reaction
DNA Fingerprinting

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36087514
DOI: 10.1016/j.fsigen.2022.102769

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