Overall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 Trial.

doi:10.1200/JCO.22.01549

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Article

Overall Survival With Maintenance Olaparib at a 7-Year Follow-Up in Patients With Newly Diagnosed Advanced Ovarian Cancer and a BRCA Mutation: The SOLO1/GOG 3004 Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Jan 2023

DiSilvestro Paul, Banerjee Susana, Colombo Nicoletta, Scambia Giovanni, Kim Byoung-Gie, Oaknin Ana, Friedlander Michael, Lisyanskaya Alla, Floquet Anne, Leary Alexandra, Sonke Gabe S, Gourley Charlie, Oza Amit, González-Martín Antonio, Aghajanian Carol, Bradley William, Mathews Cara, Liu Joyce, McNamara John, Lowe Elizabeth S, Ah-See Mei-Lin, Moore Kathleen N

Abstract excerpt

PURPOSE: In SOLO1/GOG 3004 (ClinicalTrials.gov identifier: NCT01844986), maintenance therapy with the poly(ADP-ribose) polymerase inhibitor olaparib provided a sustained progression-free survival benefit in patients with newly diagnosed advanced ovarian cancer and a BRCA1 and/or BRCA2 (BRCA) mutation. We report overall survival (OS) after a 7-year follow-up, a clinically relevant time point and the longest...

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Identifiers

PMID: 36082969
DOI: 10.1200/JCO.22.01549
PMCID: PMC9870219

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