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Article

Systematic pan‑cancer analysis identifies CDC45 as having an oncogenic role in human cancers

8 Sept 2022

Abstract excerpt

Cell division cycle 45 (CDC45) is an essential protein required for the initiation of DNA replication. In the present study, the role of CDC45 across 33 cancers was systematically investigated. It was observed that the expression of CDC45 was significantly upregulated in most cancers, exhibiting a marked negative correlation with the overall survival. Next, there was no significant difference in prognosis between...

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PMID: 36082823
DOI: 10.3892/or.2022.8400

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