Viral clade is associated with severity of symptomatic genotype 3 hepatitis E virus infections in Belgium, 2010-2018.

doi:10.1016/j.jhep.2022.08.033

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Article

Viral clade is associated with severity of symptomatic genotype 3 hepatitis E virus infections in Belgium, 2010-2018.

Journal of hepatology - 1 Jan 2023

Peeters Michael, Schenk Julie, De Somer Thomas, Roskams Tania, Locus Tatjana, Klamer Sofieke, Subissi Lorenzo, Suin Vanessa, Delwaide Jean, Stärkel Peter, De Maeght Stéphane, Willems Philippe, Colle Isabelle, Van Hoof Marc, Van Acker Jos, Van Steenkiste Christophe, Moreno Christophe, Janssens Filip, Reynders Marijke, Steverlynck Matthias, Verlinden Wim, Lasser Luc, de Galocsy Chantal, Geerts Anja, Maus Jeroen, Gallant Marie, Van Outryve Steven, Marot Astrid, Reynaert Hendrik, Decaestecker Jochen, Bottieau Emmanuel, Schreiber Jonas, Mulkay Jean-Pierre, de Goeij Sébastien, Salame Mikhaël, Dooremont Diederik, Dastis Sergio Negrín, Boes Juul, Nijs Jochen, Beyls Jan, Hens Niel, Nevens Frederik, Van Gucht Steven, Vanwolleghem Thomas

Abstract excerpt

BACKGROUND & AIMS: HEV genotype (gt) 3 infections are prevalent in high-income countries and display a wide spectrum of clinical presentations. Host - but not viral - factors are reported to be associated with worse clinical outcomes. METHODS: Demographic, clinical, and biochemical data laboratory-confirmed HEV infections (by PCR and/or a combination of IgM and IgG serology) at the Belgian National Reference...

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PMID: 36075495
DOI: 10.1016/j.jhep.2022.08.033

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