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CDC42 governs normal oviduct multiciliogenesis through activating AKT to ensure timely embryo transport

2 Sept 2022

Abstract excerpt

Ciliated and secretory cells are two major cell types that comprise the oviduct epithelia. Accumulating evidences support a role of oviductal multiciliated epithelia for embryo transport, however the mechanisms underlying this specialized cell type differentiation remain elusive. Here, we report that CDC42 depletion in oviduct epithelia hampers the morphogenesis of multiciliated cell, and results in embryo...

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PMID: 36056002
DOI: 10.1038/s41419-022-05184-y

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