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Article

Phenotypic and Genetic Studies of the Viral Lineage Associated with the Recent Yellow Fever Outbreak in Brazil.

Viruses - 19 Aug 2022

Furtado Nathália Dias, Gómez Mariela Martínez, de Mello Iasmim Silva, Fernandes Déberli Ruiz, Bonaldo Myrna Cristina

Abstract excerpt

Yellow fever virus (YFV) caused an outbreak in the Brazilian Southeast from 2016 to 2019, of the most significant magnitude since the 1900s. An investigation of the circulating virus revealed that most of the genomes detected in this period carried nine unique amino acid polymorphisms, with eight located in the non-structural proteins NS3 and NS5, which are pivotal for viral replication. To elucidate the effect...

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Identifiers

PMID: 36016440
DOI: 10.3390/v14081818
PMCID: PMC9412561

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