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Identification of CXCL10 and CXCL11 as the candidate genes involving the development of colitis-associated colorectal cancer

8 Aug 2022

Abstract excerpt

Background: Ulcerative colitis (UC) is a well-known risk factor for developing colitis-associated colorectal cancer (CAC). However, the molecular mechanism of the pathogenesis of CAC remains unclear. This study aimed to explore candidate genes involved in the tumorigenesis of CAC. Methods: GSE75214 and the Cancer Genome Atlas Program (TCGA) dataset were used to analyze the differentially expressed genes (DEGs) in...

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PMID: 36003333
DOI: 10.3389/fgene.2022.945414

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