Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions.

doi:10.1073/pnas.2122680119

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Article

Geographic patterns of koala retrovirus genetic diversity, endogenization, and subtype distributions.

Proceedings of the National Academy of Sciences of the United States of America - 16 Aug 2022

Blyton Michaela D J, Young Paul R, Moore Ben D, Chappell Keith J

Abstract excerpt

Koala retrovirus (KoRV) subtype A (KoRV-A) is currently in transition from exogenous virus to endogenous viral element, providing an ideal system to elucidate retroviral-host coevolution. We characterized KoRV geography using fecal DNA from 192 samples across 20 populations throughout the koala's range. We reveal an abrupt change in KoRV genetics and incidence at the Victoria/New South Wales state border. In...

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PMID: 35943984
DOI: 10.1073/pnas.2122680119
PMCID: PMC9388103

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