Article
Sorafenib maintenance after hematopoietic stem cell transplantation improves outcome of FLT3-ITD-mutated acute myeloid leukemia.
International journal of hematology - 1 Dec 2022
Aydin Semra, Passera Roberto, Scaldaferri Matilde, Dellacasa Chiara Maria, Poggiu Marco, Cattel Francesco, Zallio Francesco, Brunello Lucia, Giaccone Luisa, Dogliotti Irene, Busca Alessandro
Abstract excerpt
In a retrospective analysis, 21 acute myeloid leukemia patients receiving single-agent sorafenib maintenance therapy in complete remission (CR) after hematopoietic stem cell transplantation (HSCT) were compared with a control group of 22 patients without maintenance. Sorafenib was initiated a median of 3 months (IQR: 2.3-3.5) after allogeneic HSCT with a median daily dosage of 400 mg (range: 200-800) orally, and...
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