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Metagenomic profiling of ocular surface microbiome changes in Demodex blepharitis patients

22 Jul 2022

Abstract excerpt

Purpose To compare the ocular surface and meibum microbial communities of humans with Demodex Blepharitis (DB) and healthy controls. Methods Conjunctival sac and meibum samples from 25 DB patients and 11 healthy controls were analyzed using metagenomic next-generation sequencing (mNGS). Results The alpha-diversity of the conjunctival sac microbiome of the DB group (observed, Chao1, ACE) was lower than that of the...

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PMID: 35937693
DOI: 10.3389/fcimb.2022.922753

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