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Article

A CRISPR-Cas12a-based diagnostic method for multiple genotypes of severe fever with thrombocytopenia syndrome virus.

PLoS neglected tropical diseases - 1 Aug 2022

Park Bum Ju, Yoo Jeong Rae, Heo Sang Taek, Kim Misun, Lee Keun Hwa, Song Yoon-Jae

Abstract excerpt

Severe fever with thrombocytopenia syndrome virus (SFTSV) infection is commonly reported in countries of Northeast Asia including China, Japan and South Korea. The majority of the SFTS patients are elderly and the average fatality rate is more than 10%. A rapid and sensitive diagnostic method to monitor and prevent SFTSV transmission remains an urgent clinical challenge. In this study, we developed a molecular...

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Identifiers

PMID: 35917293
DOI: 10.1371/journal.pntd.0010666
PMCID: PMC9345333

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