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Identifying DUSP-1 and FOSB as hub genes in immunoglobulin A nephropathy by WGCNA and DEG screening and validation

25 Jul 2022

Abstract excerpt

Background: The mechanism of immunoglobulin A nephropathy (IgAN) is still unknown. A bioinformatics analysis is a powerful method to identify the biomarkers and possible therapeutic targets of a certain disease from related datasets. Methods: The GSE93973 dataset, obtained from the Gene Expression Omnibus (GEO) database, was used to construct a weighted gene co-expression network (WGCNA) and filter differentially...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35910761
DOI: 10.7717/peerj.13725

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