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Zoonotic Threat of G4 Genotype Eurasian Avian-Like Swine Influenza A(H1N1) Viruses, China, 2020.

Emerging infectious diseases - 1 Aug 2022

Gu Min, Chen Kaibiao, Ge Zhichuang, Jiao Jun, Cai Tianyu, Liu Suhan, Wang Xiaoquan, Jiao Xinan, Peng Daxin, Liu Xiufan

Abstract excerpt

We investigated genetic and biologic characteristics of 2 Eurasian avian-like H1N1 swine influenza viruses from pigs in China that belong to the predominant G4 genotype. One swine isolate exhibited strikingly great homology to contemporaneous human Eurasian avian-like H1N1 isolates, preferential binding to the human-type receptor, and vigorous replication in mice without adaptation.

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Identifiers

PMID: 35876682
DOI: 10.3201/eid2808.212530
PMCID: PMC9328894

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