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Article

Identification of DNA Methylation Signature and Rules for SARS-CoV-2 Associated with Age

27 Jun 2022

Abstract excerpt

Background: COVID-19 displays an increased mortality rate and higher risk of severe symptoms with increasing age, which is thought to be a result of the compromised immunity of elderly patients. However, the underlying mechanisms of aging-associated immunodeficiency against Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remains unclear. Epigenetic modifications show considerable changes with age,...

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PMID: 35866388
DOI: 10.31083/j.fbl2707204

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