Article
Mutations in DNA polymerase δ subunit 1 co-segregate with CMD2-type resistance to Cassava Mosaic Geminiviruses.
Nature communications - 7 Jul 2022
Lim Yi-Wen, Mansfeld Ben N, Schläpfer Pascal, Gilbert Kerrigan B, Narayanan Narayanan N, Qi Weihong, Wang Qi, Zhong Zhenhui, Boyher Adam, Gehan Jackson, Beyene Getu, Lin Zuh-Jyh Daniel, Esuma Williams, Feng Suhua, Chanez Christelle, Eggenberger Nadine, Adiga Gerald, Alicai Titus, Jacobsen Steven E, Taylor Nigel J, Gruissem Wilhelm, Bart Rebecca S
Abstract excerpt
Cassava mosaic disease (CMD) suppresses cassava yields across the tropics. The dominant CMD2 locus confers resistance to cassava mosaic geminiviruses. It has been reported that CMD2-type landraces lose resistance after regeneration through de novo morphogenesis. As full genome bisulfite sequencing failed to uncover an epigenetic mechanism for this loss of resistance, whole genome sequencing and genetic variant...
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