Article
CD93 orchestrates the tumor microenvironment and predicts the molecular subtype and therapy response of bladder cancer.
Computers in biology and medicine - 1 Aug 2022
Zheng Xiaonan, Xu Hang, Lin Tianhai, Tan Ping, Xiong Qiao, Yi Xianyanling, Qiu Shi, Yang Lu, Shen Bairong, Ai Jianzhong, Wei Qiang
Abstract excerpt
BACKGROUND: CD93 is newly reported to normalize vasculature and attenuate pancreatic cancer therapy response, but its role in bladder cancer (BLCA) is unknown. METHOD: The immunologic role of CD93 is analyzed across TCGA pan-cancers. The correlation between CD93 and BLCA clinical and tumor microenvironment features, predicted immunotherapy pathways, molecular subtypes, therapeutic signatures and mutation status...
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