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Genetic diversity and spatiotemporal dynamics of DENV-1 and DENV-2 infections during the 2012-2013 outbreak in Mexico.

Virology - 1 Aug 2022

Rodríguez-Aguilar Eduardo D, Martínez-Barnetche Jesús, Juárez-Palma Lilia, Alvarado-Delgado Alejandro, González-Bonilla Cesar R, Rodríguez Mario H

Abstract excerpt

Dengue fever is caused by four related dengue virus serotypes, DENV-1 to DENV-4, where each serotype comprises distinct genotypes and lineages. The last major outbreak in Mexico occurred during 2012 and 2013, when 112,698 confirmed cases were reported (DENV-1 and DENV-2 were predominant). Following partial E, NS2A and NS5 gene sequencing, based on the virus genome variability, we analyzed 396 DENV-1 and 248...

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PMID: 35779336
DOI: 10.1016/j.virol.2022.06.011

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