Article
Polymorphisms rs2010963 and rs833061 of the VEGF gene in polycystic ovary syndrome.
Revista da Associacao Medica Brasileira (1992) - 1 Jan 2022
Vicente Anna Luiza Silva Almeida, Marqui Alessandra Bernadete Trovó de, Gomes Mariana Kefalas Oliveira, Assunção-Luiz Alan Vinicius, Balarin Marly Aparecida Spadotto, Tanaka Sarah Cristina Sato Vaz, Resende Elisabete Aparecida Mantovani Rodrigues de, Lima Marco Fábio Prata, Cintra Mariangela Torreglosa Ruiz
Abstract excerpt
OBJECTIVE: The polycystic ovary syndrome is the most common endocrine disorder, characterized by the dysregulation of ovarian angiogenesis. This alteration can be related to changes in the activities of the vascular endothelial growth factor (VEGF) gene. Single-nucleotide polymorphisms have been observed in the promoter, intronic, and untranslated regions of the VEGF gene, and several studies have suggested that...
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