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Exploration of Potential Targets and Mechanisms of Fisetin in the Treatment of Non-Small-Cell Lung Carcinoma via Network Pharmacology and In Vitro Validation

13 Jun 2022

Abstract excerpt

Purpose: The morbidity and fatality rates of non-small-cell lung cancer (NSCLC) were high, although a combination of multiple treatments was used. Fisetin, a small flavonoid compound, had shown anticancer activities. Thus, we aimed at exploring the mechanisms of Fisetin in the treatment of NSCLC. Methods: TCMSP and Swiss target tools were used to screen the targets of Fisetin, and GeneCards was used to collect...

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PMID: 35733630
DOI: 10.1155/2022/2383527

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