Article
Identification of HOX signatures contributing to oral cancer phenotype.
Scientific reports - 16 Jun 2022
Padam Kanaka Sai Ram, Morgan Richard, Hunter Keith, Chakrabarty Sanjiban, Kumar Naveena A N, Radhakrishnan Raghu
Abstract excerpt
The role of evolutionarily conserved homeobox-containing HOX genes as transcriptional regulators in the developmental specification of organisms is well known. The contribution of HOX genes involvement in oral cancer phenotype has yet to be fully ascertained. TCGA-HNSC HTSeq-counts and clinical data were retrieved from the GDC portal for oral cavity neoplasms. GEO datasets (GSE72627, GSE30784, GSE37991) were...
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