Article
Levodopa ONOFF-state freezing of gait: Defining the gait and non-motor phenotype.
PloS one - 1 Jan 2022
Landes Reid D, Glover Aliyah, Pillai Lakshmi, Doerhoff Shannon, Virmani Tuhin
Abstract excerpt
BACKGROUND: Freezing in the levodopa-medicated-state (ON-state) is a debilitating feature of Parkinson's disease without treatment options. Studies detailing the distinguishing features between people with freezing of gait that improves with levodopa and those whose freezing continues even on levodopa are lacking. OBJECTIVE: To characterize the gross motor, gait, and non-motor features of this phenotype. METHODS:...
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