Article
Oral Coenzyme Q10 supplementation leads to better preservation of kidney function in steroid-resistant nephrotic syndrome due to primary Coenzyme Q10 deficiency.
Kidney international - 1 Sept 2022
Drovandi Stefania, Lipska-Ziętkiewicz Beata S, Ozaltin Fatih, Emma Francesco, Gulhan Bora, Boyer Olivia, Trautmann Agnes, Xu Hong, Shen Qian, Rao Jia, Riedhammer Korbinian M, Heemann Uwe, Hoefele Julia, Stenton Sarah L, Tsygin Alexey N, Ng Kar-Hui, Fomina Svitlana, Benetti Elisa, Aurelle Manon, Prikhodina Larisa, Schreuder Michiel F, Tabatabaeifar Mansoureh, Jankowski Maciej, Baiko Sergey, Mao Jianhua, Feng Chunyue, Liu Cuihua, Sun Shuzhen, Deng Fang, Wang Xiaowen, Clavé Stéphanie, Stańczyk Małgorzata, Bałasz-Chmielewska Irena, Fila Marc, Durkan Anne M, Levart Tanja Kersnik, Dursun Ismail, Esfandiar Nasrin, Haas Dorothea, Bjerre Anna, Anarat Ali, Benz Marcus R, Talebi Saeed, Hooman Nakysa, Ariceta Gema, Schaefer Franz
Abstract excerpt
Primary Coenzyme Q10 (CoQ10) deficiency is an ultra-rare disorder caused by defects in genes involved in CoQ10 biosynthesis leading to multidrug-resistant nephrotic syndrome as the hallmark kidney manifestation. Promising early results have been reported anecdotally with oral CoQ10 supplementation. However, the long-term efficacy and optimal prescription remain to be established. In a global effort, we collected...
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