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Article

Genome-wide association mapping within a local Arabidopsis thaliana population more fully reveals the genetic architecture for defensive metabolite diversity.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 18 Jul 2022

Gloss Andrew D, Vergnol Amélie, Morton Timothy C, Laurin Peter J, Roux Fabrice, Bergelson Joy

Abstract excerpt

A paradoxical finding from genome-wide association studies (GWAS) in plants is that variation in metabolite profiles typically maps to a small number of loci, despite the complexity of underlying biosynthetic pathways. This discrepancy may partially arise from limitations presented by geographically diverse mapping panels. Properties of metabolic pathways that impede GWAS by diluting the additive effect of a...

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PMID: 35634919
DOI: 10.1098/rstb.2020.0512
PMCID: PMC9149790

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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